Atzrodt, Jens: search on Z-Library

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1

Hydrogen Isotope Exchange - The Foundation of C-H activation and Isotope Science in Drug Discovery

Atzrodt, Jens, Derdau, Volker, Kerr, William J., Reid, Marc

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 2.33 MB

english, 2017

2

C-H Functionalization for Hydrogen Isotope Exchange

Atzrodt, Jens, Derdau, Volker, Kerr, William John, Reid, Marc

Journal:

Angewandte Chemie

Year:

2017

Language:

english

File:

PDF, 4.00 MB

english, 2017

3

C-H Functionalization for Hydrogen Isotope Exchange

Atzrodt, Jens, Derdau, Volker, Kerr, William John, Reid, Marc

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 4.00 MB

english, 2017

4

Expanded applicability of iridium(I) NHC/phosphine catalysts in hydrogen isotope exchange processes with pharmaceutically-relevant heterocycles

Atzrodt, Jens, Derdau, Volker, Kerr, William J., Reid, Marc, Rojahn, Patrick, Weck, Remo

Journal:

Year:

2015

Language:

english

File:

PDF, 8.87 MB

english, 2015

5

11th International Isotope Symposium on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds (IIS2012)

Atzrodt, Jens, Derdau, Volker, Allen, John

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2013

Language:

english

File:

PDF, 57 KB

english, 2013

6

Directed Iridium‐Catalyzed Hydrogen Isotope Exchange Reactions of Phenylacetic Acid Esters and Amides

Valero, Mégane, Becker, Daniel, Jess, Kristof, Weck, Remo, Atzrodt, Jens, Bannenberg, Thomas, Derdau, Volker, Tamm, Matthias

Journal:

Chemistry - A European Journal

Year:

2019

Language:

english

File:

PDF, 1.31 MB

english, 2019

7

Die Renaissance des H/D-Austausches

Jens Atzrodt, Volker Derdau, Thorsten Fey, Jochen Zimmermann

Journal:

Angewandte Chemie

Year:

2007

Language:

german

File:

PDF, 1.00 MB

german, 2007

8

The Renaissance of H/D Exchange

Jens Atzrodt, Volker Derdau, Thorsten Fey, Jochen Zimmermann

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 1.28 MB

english, 2007

9

13th Workshop of the Central European Division e.V. of the International Isotope Society

Volker Derdau, Jens Atzrodt, István E. Markó, Simon J. Harwood, Th. Moenius, R. Salter, B. Wietfeld, P. Burtscher, C. Zueger, Jonathan Clayden, R. Salter, K. Bordeaux, P. Burtscher, Y. Metz, Th. Moeni

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2006

Language:

english

File:

PDF, 248 KB

english, 2006

10

Fünfring-Cycloamidine – Neue farbige Heterocyclen mit ungewöhnlichen Eigenschaften. I. Synthese und spektrale Besonderheiten

Jens Atzrodt, Jörg Brandenburg, Christian Käpplinger, Prof. Dr. Rainer Beckert, Wolfgang Günther, Helmar Görls, Jürgen Fabian

Journal:

Advanced Synthesis & Catalysis

Year:

1997

File:

PDF, 551 KB

1997

11

Conception, realization and qualification of a radioactive clean room lab facility dedicated to the synthesis of radiolabeled API for human ADME studies

Loewe, Claudia, Atzrodt, Jens, Reschke, Kai, Schofield, Joe

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2016

Language:

english

File:

PDF, 325 KB

english, 2016

12

Hydrogen-Isotope Exchange (HIE) Reactions of Secondary and Tertiary Sulfonamides and Sulfonylureas with Iridium(I) Catalysts

Burhop, Annina, Weck, Remo, Atzrodt, Jens, Derdau, Volker

Journal:

European Journal of Organic Chemistry

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

13

Fünfring-Cycloamidine – Neue farbige Heterocyclen mit ungewöhnlichen Eigenschaften. II. Molekül- und Elektronenstruktur

Jürgen Fabian, Helmar Görls, Prof. Dr Rainer Beckert, Jens Atzrodt

Journal:

Advanced Synthesis & Catalysis

Year:

1997

File:

PDF, 688 KB

1997

14

Scientific Program IIS2012, Heidelberg

Atzrodt, Jens, Derdau, Volker, Allen, John

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2013

Language:

english

File:

PDF, 155 KB

english, 2013

15

Hydrogen Isotope Exchange - The Foundation of C-H activation and Isotope Science in Drug Discovery

Atzrodt, Jens, Derdau, Volker, Kerr, William J., Reid, Marc

Journal:

Angewandte Chemie

Year:

2017

Language:

english

File:

PDF, 2.33 MB

english, 2017

16

Effect of deuteration on metabolism and clearance of Nerispirdine (HP184) and AVE5638

Schofield, Joseph, Derdau, Volker, Atzrodt, Jens, Zane, Patricia, Guo, Zuyu, van Horn, Robert, Czepczor, Valérie, Stoltz, Axelle, Pardon, Magalie

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.25 MB

english, 2015

17

Highly Selective Directed Iridium-Catalyzed Hydrogen Isotope Exchange Reactions of Aliphatic Amides

Derdau, Volker, Valero, Mégane, Weck, Remo, Atzrodt, Jens, Güssregen, Stefan

Journal:

Angewandte Chemie International Edition

Year:

2018

Language:

english

File:

PDF, 1008 KB

english, 2018

18

Synthesis of isotopically labelled SGLT inhibitors and their metabolites

Volker Derdau, Thorsten Fey, Jens Atzrodt

Journal:

Year:

2010

Language:

english

File:

PDF, 709 KB

english, 2010

19

Selected Scientific Topics of the 11th International Isotope Symposium on the Synthesis and Applications of Isotopes and Isotopically Labeled Compounds

Atzrodt, Jens, Derdau, Volker

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

20

Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites

Ackerson, Timothy, Amberg, Alexander, Atzrodt, Jens, Arabeyre, Catherine, Defossa, Elisabeth, Dorau, Martina, Dudda, Angela, Dwyer, Jacquelyn, Holla, Wolfgang, Kissner, Thomas, Kohlmann, Markus, Kürze

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2019

Language:

english

File:

PDF, 768 KB

english, 2019

21

NHC-Stabilized Iridium Nanoparticles as Novel Catalysts in Hydrogen Isotope Exchange Reactions of Anilines

Valero, Mégane, Bouzouita, Donia, Palazzolo, Alberto, Atzrodt, Jens, Dugave, Christophe, Tricard, Simon, Feuillastre, Sophie, Pieters, Grégory, Chaudret, Bruno, Derdau, Volker

Journal:

Angewandte Chemie International Edition

Year:

2019

File:

PDF, 1.49 MB

2019

22

Preparation of labeled human drug metabolites and drug-drug interaction-probes with fungal peroxygenases

Poraj-Kobielska, Marzena, Atzrodt, Jens, Holla, Wolfgang, Sandvoss, Martin, Gröbe, Glenn, Scheibner, Katrin, Hofrichter, Martin

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2013

Language:

english

File:

PDF, 353 KB

english, 2013

23

Synthesis of deuterium labelled 2-bromobenzylamine by directed ortho-metalation chemistry

Jens Atzrodt, Volker Derdau

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

24

Tritiation of azido-labelled diiodo cabazitaxel (Jevtana) and docetaxel (Taxotere) derivatives to generate 3 H-photoaffinity probes

Jones, Seth, Weck, Remo, Burhop, Annina, Atzrodt, Jens, Derdau, Volker

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2018

Language:

english

File:

PDF, 538 KB

english, 2018

25

Eine unerwartete Reaktion zwischen Oxalylchlorid und atropisomeren Diaminen

Dirk Lindauer, Jens Atzrodt, Rainer Beckert, Helmar Görls

Journal:

European Journal of Organic Chemistry

Year:

1995

Language:

german

File:

PDF, 287 KB

german, 1995

26

ChemInform Abstract: Nucleophilic Substitution of 4H-Imidazoles — A Key Step in the Synthesis of Fused Imidazoles and New Chromophores.

Jens Atzrodt, Rainer Beckert, Wolfgang Guenther, Helmar Goerls

Journal:

Year:

2001

Language:

english

File:

PDF, 36 KB

english, 2001

27

ChemInform Abstract: Nucleophilic Substitution of 4H-Imidazoles by Thioles: New Starting Materials for Tetraazafulvalenes and Fused Heterocycles.

Jens Atzrodt, Rainer Beckert, Helmar Goerls

Journal:

Year:

2001

File:

PDF, 34 KB

2001

28

H/D-exchange reactions with hydride-activated catalysts

Volker Derdau, Jens Atzrodt, Wolfgang Holla

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

29

Ruthenium-Catalyzed Selective α,β-Deuteration of Bioactive Amines

Neubert, Lorenz, Michalik, Dirk, Bähn, Sebastian, Imm, Sebastian, Neumann, Helfried, Atzrodt, Jens, Derdau, Volker, Holla, Wolfgang, Beller, Matthias

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 661 KB

english, 2012

30

One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases

Kiebist, Jan, Holla, Wolfgang, Heidrich, Johannes, Poraj-Kobielska, Marzena, Sandvoss, Martin, Simonis, Reiner, Gröbe, Glenn, Atzrodt, Jens, Hofrichter, Martin, Scheibner, Katrin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 866 KB

english, 2015

31

C-H/C-D Exchange Reactions of Aromatic Compounds in D 2 O with NaBD 4 -Activated Catalysts

Derdau, Volker, Atzrodt, Jens

Journal:

Year:

2006

Language:

english

File:

PDF, 111 KB

english, 2006

32

Hydrogen–Deuterium Exchange Reactions of Aromatic Compounds and Heterocycles by NaBD4-Activated Rhodium, Platinum and Palladium Catalysts

Volker Derdau, Jens Atzrodt, Jochen Zimmermann, Carsten Kroll, Francois Brückner

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

33

Iridium-catalysed ortho-H/D and -H/T Exchange under Basic Conditions: C-H Activation of Unprotected Tetrazoles

Kerr, W J, Lindsay, David M, Reid, Marc, Atzrodt, Jens, Derdau, Volker, Rojahn, Patrick, Weck, Remo

Journal:

Chemical Communications

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

34

Hydrogen Isotope Exchange with Iridium(I) Complexes Supported by Phosphine-Imidazolin-2-imine P,N Ligands

Jess, Kristof, Derdau, Volker, Weck, Remo, Atzrodt, Jens, Freytag, Matthias, Jones, Peter G., Tamm, Matthias

Journal:

Advanced Synthesis & Catalysis

Year:

2017

Language:

english

File:

PDF, 1002 KB

english, 2017

35

The Stabilization of Lithiated Organic Compounds by Water as a Ligand – Synthesis of a New Lithium–Imidazole Complex and Regioselective Reactions with Selected Electrophiles

Jens Atzrodt, Rainer Beckert, Michael Bräuer, Karsten Nordhoff, Ernst Anders, Helmar Görls

Journal:

European Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 216 KB

english, 1998

36

Nucleophilic Substitution of 4H-Imidazolesby Thioles: New Starting Materials for Tetraazafulvalenes and Fused Heterocycles

Jens Atzrodt, Rainer Beckert, Helmar Görls

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

37

Synthesis of β-Aminonitrones by Regioselective Oxidation of 4H-Imidazoles

Jens Atzrodt, Rainer Beckert, Helmar Görls

Journal:

Advanced Synthesis & Catalysis

Year:

2000

Language:

english

File:

PDF, 62 KB

english, 2000

38

Synthesis of new axial chiral diisothiocyanates

Jens Atzrodt, Rainer Beckert, Anja Darsen

Journal:

Tetrahedron: Asymmetry

Year:

1997

Language:

english

File:

PDF, 205 KB

english, 1997

39

14th Workshop of the Central European Division e.V. of the International Isotope Society

Volker Derdau, Jens Atzrodt

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2007

Language:

english

File:

PDF, 172 KB

english, 2007

40

Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein

Duran, George E., Derdau, Volker, Weitz, Dietmar, Philippe, Nicolas, Blankenstein, Jörg, Atzrodt, Jens, Sémiond, Dorothée, Gianolio, Diego A., Macé, Sandrine, Sikic, Branimir I.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

41

Burgess Iridium(I)-Catalyst for selective Hydrogen Isotope Exchange

Burhop, Annina, Prohaska, Raphail, Weck, Remo, Atzrodt, Jens, Derdau, Volker

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2017

Language:

english

File:

PDF, 706 KB

english, 2017

42

Iridium-catalyzed Csp3-H Activation for Mild and Selective Hydrogen Isotope Exchange

Kerr, William J., Mudd, Richard J, Reid, Marc, Atzrodt, Jens, Derdau, Volker

Journal:

Year:

2018

Language:

english

File:

PDF, 363 KB

english, 2018

43

Evaluation of a P,N-Ligated Iridium(I) Catalyst in Hydrogen Isotope Exchange Reactions of Aryl and Heteroaryl Compounds

Valero, Mégane, Burhop, Annina, Jess, Kristof, Weck, Remo, Tamm, Matthias, Atzrodt, Jens, Derdau, Volker

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2017

Language:

english

File:

PDF, 444 KB

english, 2017

44

Highly Selective Directed Iridium-Catalyzed Hydrogen Isotope Exchange Reactions of Aliphatic Amides

Derdau, Volker, Valero, Mégane, Weck, Remo, Atzrodt, Jens, Güssregen, Stefan

Journal:

Angewandte Chemie

Year:

2018

Language:

english

File:

PDF, 1008 KB

english, 2018

45

Reduction of 4H-Imidazoles — Synthesis and Reactivity of 4,5-Diaminoimidazoles Bearing a Tetraaminoethene Substructure

Beckert, Rainer, Atzrodt, Jens, Görls, Helmar

Journal:

Year:

1999

Language:

english

File:

PDF, 522 KB

english, 1999

46

Nucleophilic Substitution of 4H-Imidazoles - A Key Step in the Synthesis of Fused Imidazoles and New Chromophores

Jens Atzrodt, Rainer Beckert, Wolfgang Günther, Helmar Görls

Journal:

European Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 295 KB

english, 2000

47

NHC‐Stabilized Iridium Nanoparticles as Novel Catalysts in Hydrogen Isotope Exchange Reactions of Anilines

Valero, Mégane, Bouzouita, Donia, Palazzolo, Alberto, Atzrodt, Jens, Dugave, Christophe, Tricard, Simon, Feuillastre, Sophie, Pieters, Grégory, Chaudret, Bruno, Derdau, Volker

Journal:

Angewandte Chemie

Year:

2019

Language:

english

File:

PDF, 1.49 MB

english, 2019

48

NHC‐Stabilized Iridium Nanoparticles as Novel Catalysts in Hydrogen Isotope Exchange Reactions of Anilines

Valero, Mégane, Bouzouita, Donia, Palazzolo, Alberto, Atzrodt, Jens, Dugave, Christophe, Tricard, Simon, Feuillastre, Sophie, Pieters, Grégory, Chaudret, Bruno, Derdau, Volker

Journal:

Angewandte Chemie

Year:

2019

File:

PDF, 1.49 MB

2019

49

Pd- and Pt-catalyzed H/D exchange methods and their application for internal MS standard preparation from a Sanofi-Aventis perspective

Jens Atzrodt, Volker Derdau

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2010

Language:

english

File:

PDF, 352 KB

english, 2010

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